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Grade 2 acne typically involves:

  1. Close comedones only

  2. Many more open and closed comedones

  3. Minor breakouts only

  4. Varying degrees of redness

The correct answer is: Close comedones only

Grade 2 acne typically involves close comedones only. This type of acne is characterized by a mix of both closed comedones (whiteheads) and open comedones (blackheads). In Grade 2 acne, there are usually no inflammatory papules or pustules present, which distinguishes it from more severe grades of acne. Grades 3 and 4 acne tend to involve more inflammation and varying degrees of redness, which are not typically seen in Grade 2 acne. Minor breakouts are not representative of Grade 2 acne, as this grade specifically refers to the presence of both closed and open comedones.